Diseases

Research Journal: May/June 2013

A review of the literature on how laminitis develops was recently published in the Equine Veterinary Journal. The authors looked at the literature concerning the various experimental models of laminitis, the mechanisms for inflammatory (sepsis) and metabolic (endocrinopathy) laminitis and how contralateral limb laminitis and pasture-associated laminitis might fit into these forms of disease.
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Laminitis Drug Is Proving Effective; FDA Clinical Trial Needs More Cases To Treat

Laminil is the first injectable drug treatment for acute and active chronic laminitis that inhibits the inflammatory response and the laminitis cascade. Laminil can treat both acute laminitis and active chronic laminitis. The drug is a mast cell stabilizer that inhibits inflammatory mediators and other chemicals from being released from the mast cell in excess. When the inflammatory mediators are not released in excess, then the laminitis cascade is broken/halted, and the horse is able to heal and recover.
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