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Researchers studied the specific lamellar pathology associated with laminitis caused by equine Cushing’s disease, also called pituitary pars intermedia dysfunction (PPID). Hooves of 26 horses and ponies were collected following euthanasia or processing for slaughter and divided into those with signs of PPID and laminitis, those with PPID and no clinical signs of laminitis and controls with no clinical signs of PPID or laminitis. Hoof tissues were examined microscopically and circulating insulin, cortisol and glucose were measured.
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